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6.872/HST.950  Biomedical Computing

Fall 2010

Instructors: Peter Szolovits, Gil Alterovitz

Lecture:  TR9.30-11  (32-144)        

Information: 

The US is about to invest at least tens of billions of dollars in healthcare information technology (HIT), hoping to create the information base for improving access to care, continuity of care, medical decision making, and reduction in errors. At the same time, we hope to make more rational the delivery of care, providing the most effective and least expensive interventions possible. This shift, if it is to be accomplished successfully, will require not only vastly improved infrastructure but also improved methods of learning from experience.

Contemporary medical care requires health care providers (and patients and their families) to know a great deal about the diseases, genetic predispositions, signs and symptoms, treatments and medications of each individual. To exploit the potential contributions of improvements in our understanding of genomics, proteomics and the “new biology,” we must combine such data with the clinical data that represent the patient’s phenotype. We must also develop new analytical methods to find the important relationships among these data, and then apply them in many settings to improve health care.

These needs form an intriguing engineering challenge described in this class, along with methods and practices aimed at their solution.

This class will serve as an introduction to the computing challenges in health care. We present the nature of contemporary health care, the types of data available for guiding decision making, research and analysis, the growing body of biological data and knowledge and underlie health care, and methods to develop models that can enhance applications from decision support to clinical research. We also look at applications of these ideas in electronic medical records, personal health records, telemedicine for developing countries, pubic health surveillance, and institutional and national scale infrastructures. Many of these latter topics will be presented by guest lecturers who are leaders in their fields.

We use many chapters from the text edited by Edward H. Shortliffe and James J. Cimino, Biomedical Informatics: Computer Applications in Health Care and Biomedicine, 3rd Edition, Springer, 2006. It is available at many places, including Amazon, and you should obtain a copy as soon as possible. We will also provide many papers on the Stellar site to cover additional topics.

Announcements

Course Evaluation

As I mentioned, Eta Kappa Nu conducts course evaluations for Course 6 classes each semester. These are not only helpful in puffing up or bruising faculty egos, but also in helping to improve classes and guiding future students to take classes most appropriate to their interests. I urge you to participate in this year's evaluation of 6.872/HST.950 by starting at
http://sixweb.mit.edu
Thank you.

Announced on 07 December 2010  1:42  p.m. by Peter Szolovits

Schedule of Student Project Presentations

I have put together the following schedule for the student presentations on December 7 and 9:
12/7 12/9
Parama Pal, Amy Wooten Julie Hermann, Ashish Kothari
Anoop Rao Ekavalia Mishra, Priya Parayanthal
Asha Radhakeesoon, Marzieh Namazi Keone Hon, Kendell Clement
Vaibhav Patil Yuan Luo
Each single student will have a 15 minute slot, including time to set up and take questions, and each pair will have 25 minutes. That fills our two class sessions, so please plan to make presentations that are no longer than 10-12 minutes for individuals and about 20 minutes for pairs. If I have accidentally omitted anyone, please let me know ASAP.

Announced on 02 December 2010  9:15  a.m. by Peter Szolovits

Additional readings for Tue Nov 9

Please note that I have posted two review papers on imaging informatics for the class next Tuesday.

Announced on 05 November 2010  3:00  p.m. by Peter Szolovits

Readings for Hamish Fraser's lecture, Nov. 2

Please note that there are three new papers posted related to Dr. Fraser's upcoming lecture. Please read them before class.

Announced on 01 November 2010  12:01  a.m. by Peter Szolovits

Use Class Forum to help form project teams!

One students suggested that the Forum could be a useful vehicle for coordinating among you to form teams for the project. I see that a few have started to do that, but it may be helpful for others as well.

Announced on 28 October 2010  3:39  p.m. by Peter Szolovits

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