- How to use the Hemodynamic Response Function (HRF) Plot The plot is based on a specific HRF function model (cf: Mark S. Cohen, "Parametric Analysis of fMRI Data Using Linear Systems Methods", NeuroImage, 6, 93-103, 1997) under no noise conditions. The value of the functions are arbitrary on units. If you click the 'Plot individual condition' menu, the HRF of each condition and their average (blue dash line) will be plotted on the respective condition row in different color. If you click the 'Plot combined condition' menu, the HRF of all condition will be plotted on all condition rows in different color. The Red dot average line represents the combined conditions average over the same time points as the individual condition.