From the point of view of the distributor, all the Hyphos nodes out there are 'inside' the Bridge. All communications from the amulets are done with asynchronous callbacks, and are not guaranteed to occur within any particular amount of time, but are considered reliable.
From the point of view of the amulets, the bridge is just another amulet. All communication in the initial implementation will be between true amulets and bridges. That is, there will be no amulet-amulet communication other than routing amulet-bridge communications.