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5.54/7.540/20.948  Frontiers in Chemical Biology

Fall 2008

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Professors: Barbara Imperiali, Sarah O'Connor

TA: Lesley-Ann Giddings

Lecture:  MW10-12  (32-124)        

Subject Description: 

Introduction to current research at the interface of chemistry, biology, and bioengineering. Topics may include metabolic pathway engineering, protein engineering, mechanisms of DNA damage, RNA structure and function, macromolecular machines, protein misfolding and disease, metabolomics, imaging of biological processes, and methods for analyzing signaling network dynamics. Lectures are interspersed with class discussions and student presentations based on current literature.

Announcements

Monday's Lecture (12/1)

A number of handouts have been posted.
In particular, 2 papers for Ram Sasisekharan's lecture have been posted in the class handouts section.

PLEASE READ THEM- this is going to be a great lecture and we would like to have significant
participation/questions from all of you. Attendence and participation yesterday was lower than I had hoped.

Thanks.
Sarah

Announced on 25 November 2008  2:47  p.m. by Sarah O'Connor

The Double Helix

Just a reminder, today we are assigning your person to "defend" for the discussion on wednesday. SO please make sure that you are in a group.

Also, we ask that only those of you registered for credit attend on wednesday- listeners, see you the following monday.
Thanks-
Sarah

Announced on 24 November 2008  7:41  a.m. by Sarah O'Connor

Announcements: 11/20

Hello everyone:

First, Angela Koehler will be presenting on screening collections and screening assays on Monday (a little out of order from the syllabus- but she is an expert in this so its worth it!!). A paper she recommended is posted in the class handouts section.

Second, please make sure you are in a group to discuss the Double Helix video by Monday (the discussion will be wednesday). We will assign the person you are going to defend on Monday.

The DVD is available from Elizabeth Fong (efong@mit.edu).

Slides from the past weeks presentations will be up shortly as soon as we get copies of them.

Sarah

Announced on 20 November 2008  10:22  a.m. by Sarah O'Connor

Handouts Posted 10/29/08

Hello everyone-
A lot of handouts have been posted.
Tony Sinskey's lecture and my updated lecture notes posted under Class Handouts
JM and Jens presentations posted under Class presentations
Some papers posted under additional reading

All are under the Biomaterials and Biopolymers topic.

And there IS class on monday- see you then.
Sarah

Announced on 29 October 2008  7:19  p.m. by Sarah O'Connor

Upcoming Seminar of interest to the CBi interface Community

Professor Peter J. Sadler
University of Warwick. His talk is entitled "Using Metal Coordination
Chemistry to Design New Medicines."

The 2008 Alan Davison Lecture in Inorganic Chemistry, on Wednesday, October 29, 2008 at 4:00PM in Room 6-120.


Announced on 26 October 2008  7:07  p.m. by Barbara Imperiali

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