7.89/CSB.100  Topics in Comp & Sys Biology

Dear students,

You should have received an email from the Evaluations office
with a link for evaluating 7.89/CSB.100 (if not, please email Jacquie at
csbphd@mit.edu and she will figure it out).  Please take the time to
complete your evaluation of the course.  I and the other instructors
really appreciate the feedback, and it is of course very helpful to future
generations of students who are considering adding this class.
(It is especially helpful if we get 100% participation, which we often have
had in the past.)  Thanks taking the time.

Have a great winter break.

Cheers,

Chris

Hi all,

fyi I have posted the two papers that we will discuss next week.
Both are related to the 1000 genomes project, a "big science" project
which was recently completed.
Other prominent recent examples of big biology include the ENCODE
project and TCGA.  I have also posted some commentaries on the ENCODE
project and big science which are easy reading.
Have a great Thanksgiving.
Cheers,
Chris

oops!
Brian, your assigned paper is #11 Win and Smolke, since there is no paper 4.

Hi all,
As discussed in class, in addition to the Elowitz/Leibler and Chau et al papers
that we will all read, each of you is asked to read one additional synthetic biology
paper, and you will write a short critique of the paper due at start of class Friday
(instructions for the writing assignment are posted).
The additional paper assignments (made based on alphabetical order
of last names) are as follows:

Maria 1 - Auslander et al
Esha 2 - Cantone et al
Diego 3 - Chan et al
Brian 4 - Chau et al
Rotem 5 - Kramer et al
Noah 6 - McMillen et al
Natasha 7 - Mondragon et al
Jonathan 8 - Saeidi et al
James 9 - Tabor et al
Joy 10 - Tigges et al

All papers are posted on the course website.

(You may swap papers with each other by mutual agreement,
so long as everyone ends up with a different paper.)

Cheers,

Chris

Hi all,

Again, your graded fellowship proposal papers are available for pickup in the
box on top of the filing cabinet in 68-271. 

Also, PLEASE read the supp info for the Ingolia paper (posted), which
includes a lot of important information and controls for the method.

And please bring any questions about sequencing technologies that don't get
answered Friday to next week's discussion (metagenomics), which also involves
sequencing.

Enjoy the papers.

Cheers,

Chris