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20.440  Analysis of Biological Networks

Fall 2008

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Hunter and Borg (2003) Nat Reviews Mol Cell Biol. 4:237-243

Instructors: Peter C Dedon, Bevin P Engelward, John M Essigmann, Leona D Samson, Ram Sasisekharan

TA: Carol Xiaoying Koh

Lecture:  WF 4-5.30 pm  (56-602)        

Information: 

Analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis placed on the basic biochemical and biophysical principles that govern these processes, whereby the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. Examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular-cellular-tissue-organ level functions. Chemical and quantitative view of the interplay of multiple pathways as biological networks. Preparation of a unique grant application in an area of biological networks.

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