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9.S913  Spec Subj Brain & Cog Sciences

Spring 2012

Instructors: Susan Gabrieli, Tom Zeffiro, Satrajit Ghosh, Christina Triantafyllou, Sheeba Arnold Anteraper, John D. E. Gabrieli

Lecture:  M EVE (3-6 PM)  (46-4062)        

Information: 

Overview

This course is an intensive introduction to the issues associated with using structural and functional MRI in a range of research applications. Presentations will cover both theory and practice related to the basic principles of MRI measurement, techniques for stimulus presentation and response recording in high magnetic fields, basic statistical methods, individual subject experimental design and analysis techniques, group design and analysis techniques, study design principles and guidelines for reporting neuroimaging studies.

The level of the presentations will be appropriate for both early and experienced investigators planning to use measures of brain structure and function in both clinical and basic studies. Each 3 hour meeting will include lecture and laboratory time. The course website will provide guidance for subsequent self-study.

The course will focus on using SPM8, FSL and Nipype for preprocessing, statistical modeling and visualization of data associated with a range of basic and clinical fMRI experimental designs. While the primary emphasis will involve using the core SPM8 programs for these purposes, there will also be extensive discussion of a variety of software tools that extend the power of SPM8. Some of these tools facilitate fMRI quality assurance through artifact detection and mitigation at various analysis stages. Other tools support a variety of data visualization methods, including MRIcron, xjView, FSLview, and FreeSurfer.

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