| phenoModel {nlme} | R Documentation |
A model function for a model used with the Phenobarb data.
This function uses compiled C code to improve execution speed.
phenoModel(Subject, time, dose, lCl, lV)
Subject |
an integer vector of subject identifiers. These should be sorted in increasing order. |
time |
numeric. A vector of the times at which the sample was drawn or the drug administered (hr). |
dose |
numeric. A vector of doses of drug administered (μg/kg). |
lCl |
numeric. A vector of values of the natural log of the
clearance parameter according to Subject and time. |
lV |
numeric. A vector of values of the natural log of the
effective volume of distribution according to Subject and
time. |
See the details section of Phenobarb for a description
of the model function that phenoModel evaluates.
a numeric vector of predicted phenobarbital concentrations.
Jose Pinheiro jose.pinheiro@pharma.novartis.com and Douglas Bates bates@stat.wisc.edu
Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer. (section 6.4)