% An example using the resume style option
% By Stephen Gildea 15 June 87

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\name{\huge \em Carolyn Jean Smith}

\addresses
{{\bf Home Address} \\
76 Lexington Ave.,~Apt.~1 \\
Somerville, MA 02144}
{{\bf Phone and Email} \\
(617) 628-0406 \\
cjsmith@mit.edu}

\begin{llist}
\sectiontitle{Experience}
\employer{Arqule Corporation and Brandeis University}
\location{1996--present}
As consultant to Arqule Corporation and Visiting Scientist at
Brandeis, worked on a joint project between Arqule Corporation and
Brandeis on a project involving synthesis of novel protease inhibitors.
Designed an enzyme kinetics laboratory; developed, ran, and did
troubleshooting of assays to test synthetic inhibitors of thrombin and
other enzymes; performed and presented kinetic analyses 
of the results. 

\employer{Dana Farber Cancer Institute, Dept. of Cancer Pharmacology}
\location{1996--1998}
Under the direction of Dr. Miyako Abe, cultured MCF-7 cells and
purified DF3 protein for use in research into the role of DF3 in
cellular function. Responsibilities included Laboratory Safety
Officer, Radiation Safety Officer, laboratory management, ordering,
troubleshooting and maintenance of equipment, conducting experiments. 
Techniques included cell culture, FPLC, 
Western immunoblotting, plasmid transfection, and affinity
chromatography, PCR, phage library screening, DNA and plasmid
purification. Trained and supervised summer student.

\employer{Tufts University, Dept. of Anatomy and Cell Biology}
\location{1995}
Held the position of research technician under the direction of Dr.
Mary K. Murray. Techniques included lectin chromatography and
electrophoresis, DNA cloning, PCR, and DNA sequencing.

\employer{Massachusetts General Hospital, Dept. of 
Hematology-Oncology, and Brigham and Women's Hospital, Dept. of Experimental 
Medicine} \location{1987--1994}
Held the position of research technologist under the direction of Dr. Stuart 
Lind. Responsibilities: Safety Officer, Radiation Safety Officer, lab 
management, experimental design, conducting experiments, and
supervision and training of incoming technician.  Techniques included protein 
purification, affinity and ion exchange chromatography, 
ELISAs, SDS-PAGE, immunoblots, antibody preparation, small animal 
surgery, histological staining of rat and human tissue 
preparations, enzyme kinetics experiments (synthetic substrate assays), 
fibrinolysis experiments using fibrinogen or whole plasma and I$^{125}$, and
cell culture.


\sectiontitle{Publications}
``Actin Stimulates Plasmin Generation by Tissue and Urokinase-Type
Plasminogen Activators,'' by Stuart E. Lind and Carolyn J. Smith. {\em
Archives of Biochemistry and Biophysics}, vol. 307, no. 1, Nov. 15,
1993.

``Oxidative Inactivation of Plasmin and Other Serine Proteases by
Copper and Ascorbate,'' by Stuart E. Lind, Jonathan R. McDonagh, and
Carolyn J. Smith. {\em Blood}, vol. 82, no. 5, Sept. 1, 1993.

``Actin Accelerates Plasmin Generation by Tissue Plasminogen
Activator,'' by Stuart E. Lind and Carolyn J. Smith. {\em Journal of
Biological Chemistry}, vol. 226, no. 26, Sept. 15, 1991.

``Actin Is a Noncompetitive Plasmin Inhibitor,'' by Stuart E. Lind and
Carolyn J. Smith. {\em Journal of Biological Chemistry}, vol. 266, no.
8, March 15, 1991.

\sectiontitle{Education}
\employer{Massachusetts Institute of Technology},
B.S.,  Life Sciences, 1987

\end{llist}
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